Almost each of us had to fight such diseases that require the use of antibacterial drugs to achieve the therapeutic effect.
They are aggressive drugs in relation to microflora.That is why the question arises of how soon you can drink alcohol after antibiotics, since many would not want to refuse wine, cognac, beer, vodka for a long time.
The question is ambiguous and there is no direct monosyllabic answer to it.There are different opinions in the media.Some during the holiday with a feast consider it more correctly to refuse to drink alcohol, based more on a hunch than reliable information from authoritative sources.Such a person in the company causes sympathy and understanding, usually no one persuades him to drink.However, there are times when someone refers to an article in which the doctor popularly explains that it does not always interfere with the recovery process.
Why you do not need to drink medicines with alcohol
As you know, smoke does not happen without fire.Doctors can, from a scientific point of view, justify the ban on the use of antimicrobials and the use of vodka or beer at the same time.Moreover, they argue that it is possible to take antibiotics after alcohol through a strictly defined period of time.Specialists appeal to the following facts:
- Ethanol at the biochemical level significantly reduces the therapeutic effect of antimicrobials;
- The combination of alcohol with drugs of the antibacterial group causes toxic damage to the liver cells, as well as other internal organs;
- The use of alcohol inhibits immunity, has a destructive effect on health, which during drug therapy is extremely undesirable.
The above arguments have a rational grain.The biochemical processes occurring in the body are extremely complex and also balanced, so the saturation of the tissues of internal organs with such a biologically active connection as ethyl alcohol cannot but affect the metabolism.Alcohol can really significantly reduce the therapeutic effect of drugs.It either destroys the atomic structure of the active substance, or prevents the reaction of drugs with the proteins of pathogenic microorganisms.Moreover, alcohol can provoke accelerated excretion or complicate the absorption of drugs.Thus, there is a decrease in the effectiveness of therapy, or undesirable side symptoms develop.
Impact on the function and state of the liver
Scientific research and practice of clinical medicine confirm the destructive effect on the liver combination of antimicrobial drugs with alcohol.That is why the instructions for the use of drugs indicate contraindications and a side effect on this extremely important body.For patients with chronic liver diseases, many drugs are not available.If you combine antimicrobial drugs and alcohol, then the negative effect will become double.After how much to drink alcohol after a course of antibiotics depends on the general condition of the body and its ability to restore.
Under the influence of enzymes, ethanol is split to water and carbon dioxide, but not immediately, but bypassing the intermediate stage of the formation of an extremely toxic compound - acetaldehyde, which is a tissue poison.The faster the breakdown of alcohol goes, the less harm it does to the body.However, with the simultaneous presence of antimicrobial drugs in the tissues of the internal organs of alcohol, alcohol catabolism is significantly slowed down due to the inhibition of the production of the enzyme alcohol dehydrogenase necessary to complete the reaction of the splitting of ethanol to simple compounds.
Ethanol does not interact directly with antibiotics
To find out how alcohol acts on drugs, and also after how many days you can drink alcohol after the end of the antibiotic course, laboratory experience was made.At first, scientists conducted animal experiments, and then invited volunteers who were offered to undergo a therapeutic course using antibacterial drugs.Participants equally divided into two groups.Representatives of the first of them during the experiment were offered alcohol, the second was not.The main goal that the organizers tried to achieve is to establish the effect of ethanol on the biological activity of drugs.
The results of the experiment showed that most antibacterial drugs are slightly or not at all interacted by ethyl alcohol - it practically did not reduce the effectiveness of the drugs used.This conclusion was taken after studying and comparing the results of antibacterial drug therapy between two groups.They were identical.The difference did not exceed the permissible error.The speed of absorption, distribution in the tissues of internal organs, as well as the withdrawal of active substances, was approximately the same.
However, hasty conclusions should not be made that the simultaneous use of antibiotics and alcohol is completely safe.Experts are asked to take into account some nuances:
- The experiment was isolated and not confirmed by other studies, so you should not insist on safety a combination of drugs and alcohol;
- Small doses of alcoholic beverages were offered experimental, and in real life moderation in the use of vodka and beer is rare quite rarely;
- The studies concerned only the interaction of drugs with ethanol, the influence of this combination on the state of the internal organs was not studied, so it is impossible to deny a negative effect.
This was the first trial step to a complete answer to an important question about how much you can drink alcohol after a course of antibiotics, so there are no final and unambiguous results.
Reasons to refuse to drink during treatment
Clinical medicine has the full right to assert that combination of alcohol and drugs should be avoided.Even if their mutual action is not properly studied, then the influence of ethanol on health is known enough to come to certain conclusions.It is impossible to deny that:
- Alcohol violates metabolic processes if you drink regularly;
- Ethanol provokes an increase in sugar in the bloodstream;
- drinking alcohol leads to physical and nervous exhaustion;
- The risk of an allergic reaction increases by an order of magnitude.
Each person has individual characteristics of internal biological processes, so it is almost impossible to predict the reaction of the body, but it will hardly be positive.
Interaction of alcohol with antimicrobial drugs
According to the experiment, the reception of drinks that contain alcohol does not affect the pharmacological properties of most antimicrobials and does not provoke significant side effects.However, there are antimicrobial drugs that cannot be taken categorically with alcohol, because this combination leads to really dangerous consequences.
Only after a few days you can drink alcohol after antibiotics that affect metabolism.For example, drugs such as cimetidine, ketoconazole, aructs and analogues require the participation of the enzyme in the biochemical reaction of the necessary also to split ethanol.Its reserves are limited.When using significant doses of ethanol, conflict occurs.The enzyme simply begins to lack either for interaction with the medicine or for reaction with ethyl alcohol.In the first case, we will definitely observe a decrease in the therapeutic efficiency of the use of the drug, plus possible allergic reactions and increased side effects of the drug.If you do not split ethanol, then you cannot avoid acute intoxication with all the ensuing consequences.That is why it is impossible to take antimicrobials of this species at the same time with alcohol.
Disulfir is the main reason for the ban on drinking alcohol during antimicrobial therapy.Introducing the catabolism of ethanol in the body leads to the accumulation of previously mentioned vinegar aldehyde - acetaldehyde.This is a potent toxin that has a global negative effect on the body.The most frequent and unpleasant signs of intoxication:
- nausea with bouts of vomiting;
- indigestion;
- acute headache;
- abundant sweating;
- general weakness, dizziness;
- tachycardia;
- increasing pressure.
Agree that such a physical condition most clearly proves the thesis that you need to use antibiotics after a course of alcohol a few days in a few days so that ethanol and its toxic decay products have managed to exit the body naturally.
By the way, Disuphum-like reaction is called that thanks to the drug for drug prohibiting therapy for chronic alcoholism-disulfiram.Its use makes alcoholics refuse to drink alcohol precisely due to the development of panic fear of symptoms of acute intoxication.The drug is administered into the subcutaneous layer (implanted), from where it gradually enters the body, and blocks the development of the enzyme responsible for the splitting of ethanol.
What complications to wait
After how long you can calmly drink alcohol after the course of antibiotics depends on the antimicrobial drug (the speed of its assimilation and excretion), as well as the individual characteristics of human metabolism.
Doctors emphasize that the ban does not apply only to a glass of cognac or vodka.You need to forget about wine, beer, low alcohol drinks.Moreover, ethyl alcohol is often contained in other food products, as well as in drugs, so you should pay attention to this aspect.
Often you can hear that someone's acquaintance used alcohol and took antimicrobial drugs, without any negative consequences.However, no one knows what happened to the body of this person, how effective the treatment turned out to be, how long it lasted, how he now has business with a state of health.Meanwhile, in the practice of clinical medicine, many cases have been recorded when people did not adhere to recommendations on how much to drink alcohol after antibiotics, but consumed it during the treatment process, and as a result became victims:
- impaired liver work;
- anaphylactic shock;
- failures in the work of the brain and central nervous system in general (severe headaches, accompanied by dizziness, nausea with vomiting attacks, convulsive attacks);
- gastrointestinal diseases;
- sleep functions;
- increased pressure;
- negative skin reactions (dermatitis);
- heart rhythm disturbances;
Our natural filter is most suffered by the liver.Despite the possibility of renewal of cells, it turns out to be such a strong negative effect that it ultimately loses its functionality.
The last word in the dispute about the combination of alcohol and antibiotics
After the end of drug therapy, you need to withstand several days before starting the use of alcoholic beverages.This is due to the removal of drugs of medicines from the body, and this requires a certain amount of time.In all drugs, the time for achieving maximum concentration in the blood and excretion is different.This is always indicated in the instructions.
Alcoholic drinks are not recommended at one time not only with antimicrobial agents, but also with other drugs.However, antimicrobial drugs are one of the few that are under a categorical ban.If you are going to undergo a medical treatment, then be sure to ask the attending physician - after how much you can drink alcohol after antibiotics.
Despite the fact that the expert opinion of experts about the admissibility of the simultaneous use of alcoholic beverages and antibacterial drugs have been divided (excluding those drugs that are clear restrictions), most doctors are inclined to the conclusion that in the process of treatment, it is better to refuse to drink alcohol.
In any case, alcohol is far from the product, for the sake of which it is worth risking health, even if the risk seems insignificant.Nothing terrible will happen if you become an avid teetotaler for 2 weeks.Even the body of a healthy person grazes in front of alcohol over time.Long drinking alcohol leads to the development of a large number of various somatic and mental disorders.If a person does not refuse alcohol during illness, then we can say with confidence that physical and mental degradation will accelerate on this period of time.Even if you could drink alcohol simultaneously with medicines, you still do not need to do this.Ethanol is poison, and how much vodka has broken fate cannot be counted.